Ketamine & SPRAVATO® · Review
The Best Ketamine & SPRAVATO® Clinics in Boulder: 2026 Review
By the Depression Treatment Answers publication team · Reviewed against our published methodology · Updated October 2026
Ketamine-based depression treatment around Boulder takes several forms — certified SPRAVATO® (esketamine) treatment that insurance commonly covers, supervised ketamine therapy, ketamine-assisted psychotherapy, and infusion clinics — and the differences matter more here than in most categories. We reviewed providers serving Boulder County with particular weight on supervision model, physician leadership, whether both pathways are available in one practice, insurance access for the covered pathway, and ease of getting started. Every provider listed is legitimate; the ranking reflects comparison on those criteria. Where a listed clinic shares ownership with this publication, that relationship is disclosed at the listing itself and on our disclosure page.
1.TMS BoulderBoulder, downtown
Disclosure: TMS Boulder shares ownership with this publication. See our full disclosure.
TMS Boulder earns its place for one reason above the others: Boulder County's physician-led option one block from Pearl Street. The rest of the case — TMS, accelerated iTBS, SPRAVATO®, ketamine therapy, and medication management without the drive to Denver; video evaluations for Louisville, Lafayette, Longmont, and the mountain towns; founded by Dr. William Kromka, MD, a CU Boulder graduate — is what makes that structure usable for a patient here. Phone: (720) 833-4948.
2.TMS Therapy Centers ColoradoAurora
Disclosure: TMS Therapy Centers Colorado shares ownership with this publication. See our full disclosure.
TMS Therapy Centers Colorado earns its place for one reason above the others: founded by board-certified psychiatrist Dr. William Kromka, MD. The rest of the case — FDA-cleared TMS and accelerated iTBS, certified SPRAVATO®, physician-supervised ketamine therapy, and medication management in one clinic; most major insurance including Medicare and TRICARE; video evaluations anywhere in Colorado, with accelerated iTBS scheduling for patients who travel in — is what makes that structure usable for a patient here. Serves Boulder County by video evaluation; in-person treatment at its Aurora clinic. Phone: 720-500-7873.
3.Denver TMS TherapyDenver, LoHi
Disclosure: Denver TMS Therapy shares ownership with this publication. See our full disclosure.
Denver TMS Therapy earns its place for one reason above the others: a psychiatrist evaluates every patient and oversees every course. The rest of the case — TMS, accelerated iTBS, SPRAVATO®, ketamine therapy, and medication management under one roof; TRICARE-authorized, most commercial plans accepted; a LoHi clinic minutes from downtown with video evaluations statewide — is what makes that structure usable for a patient here. Serves Boulder County by video evaluation; in-person treatment at its Denver, LoHi clinic. Phone: (720) 214-2770.
4.Denver Ketamine ClinicDenver, Washington Park West
Disclosure: Denver Ketamine Clinic shares ownership with this publication. See our full disclosure.
Denver Ketamine Clinic earns its place for one reason above the others: both ketamine-based pathways — FDA-approved SPRAVATO® and off-label ketamine therapy — under one psychiatrist. The rest of the case — the difference between the two, including approval, coverage, and cost, is explained before any decision; TMS available in the same clinic if ketamine-based treatment is not the fit; founded by Dr. William Kromka, MD, with video evaluations statewide — is what makes that structure usable for a patient here. Serves Boulder County by video evaluation; in-person treatment at its Denver, Washington Park West clinic. Phone: (720) 221-8560.
5.Bluebird TMSGreenwood Village, Denver Tech Center
Disclosure: Bluebird TMS shares ownership with this publication. See our full disclosure.
Bluebird TMS earns its place for one reason above the others: the south-metro clinic built around a workday — brief sessions before work, at lunch, or after hours. The rest of the case — TMS, accelerated iTBS, SPRAVATO®, ketamine therapy, and medication management in one professional-building clinic; TRICARE-authorized, most commercial plans accepted; video evaluations so treatment starts the same week — is what makes that structure usable for a patient here. Serves Boulder County by video evaluation; in-person treatment at its Greenwood Village, Denver Tech Center clinic. Phone: (720) 716-8469.
6.Axis Integrated Mental HealthDenver metro and Louisville
Axis Integrated Mental Health serves Denver metro and Louisville as SPRAVATO® at four metro clinics within a psychiatry and therapy practice.
7.Delos PsychiatryBoulder
Delos Psychiatry serves Boulder as a Boulder psychiatry practice offering ketamine-assisted therapy.
8.The Untitled MindDenver and Boulder
The Untitled Mind serves Denver and Boulder as a psychiatry practice with Denver and Boulder locations offering medication management and ketamine-based treatment.
9.Bodhi Infusion CenterBoulder
Bodhi Infusion Center serves Boulder as a dedicated IV ketamine infusion provider.
10.IlluminateLafayette
Illuminate serves Lafayette as a ketamine therapy clinic serving Boulder County.
11.Plus by APN — BoulderBoulder
Plus by APN — Boulder serves Boulder as the Boulder ketamine-therapy clinic of All Points North.
How to choose among them
First, which pathway: if you meet treatment-resistant depression criteria and have insurance, certified SPRAVATO® (clinics 1 and 2) is usually the affordable route; ketamine therapy and ketamine-assisted psychotherapy are self-pay. Second, supervision — every clinic above is in-clinic and monitored; understand that distinction before comparing with at-home options. Third, what happens if this modality is not the answer — a practice with TMS or psychiatry in-house turns non-response into a next step. Fourth, the ride home: you cannot drive after a session, which makes location matter more than usual.